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17-hydroxyprogesterone in serum/plasma

Indications: - evaluation of congenital adrenal hyperplasia - evaluation of corpus luteum contribution of progestational activity during pregnancy Reference interval: - premature infant: 26-568 ng/dL - newborn 7-77 ng/dL - prepubertal children : 3-90 ng/dL - adults: 27-199 ng/mL - pregnancy: 200-1200 ng/dL - postmenopause: < 70 ng/dL Clinical significance: - 17-hydroxyprogesterone has a circadian variation with highest serum values in the AM - leuteal phase variation indicates corpus luteum activity Increases: - congenital adrenal hyperplasia from 21-hydroxylase deficiency Decreases: - male pseudohemophrodism - Addison's disease Methods: - RIA Specimen: - early morning specimen preferred - freeze immediately - store at 4 degrees C for up to 4 days

Related

17-hydroxyprogesterone (Duralutin, Makena, Prodrox)

General

17-hydroxyprogesterone in body fluid

References

  1. Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed, WB Saunders, Philadelphia, 2006
  2. Lab Tests Online: 17-Hydroxyprogesterone http://labtestsonline.org/understanding/analytes/6-17hydroxy/tab/test
  3. 17-Hydroxyprogesterone, Ser/Pla Laboratory Test Directory ARUP: 70005
  4. Panel of 4 tests Laboratory Test Directory ARUP: 92330
  5. 17-Hydroxyprogesterone Quant, MS/MS, Ser Laboratory Test Directory ARUP: 92332
  6. Panel of 3 tests Laboratory Test Directory ARUP: 2002029
  7. Panel of 4 tests Laboratory Test Directory ARUP: 2002281
  8. Panel of 5 tests Laboratory Test Directory ARUP: 2002282
  9. Panel of 4 tests Laboratory Test Directory ARUP: 2002283